| | Day | Time | | Opponent | Score | | Record |
| February |
| | 12 | 1:30PM | @ | Campbellsville University | RAIN | | | |
| | 15 | | vs. | Campbellsville University | L-2-6 | | 0-1 |
| | 16 | 1:00PM | vs. | Taylor University | W-4-3 | | 1-1 |
| | 17 | 12:00PM | @ | Cumberland Univ. | L-0-9 | | 1-2 |
| | Cumberland and IUSE played a doubleheader on Friday 17 Feb 06. Saturdays game with IUSE, and Sundays game vs. Mt. Mercy were cancelled due to snow. |
| | | 2:00PM | @ | Cumberland Univ. | L-0-9 | | 1-3 |
| | 25 | 12:00PM | vs. | Ohio Dominican College | W-12-9 | | 2-3 |
| | 26 | 12:00PM | vs. | Illinois Institute of Technology | L-1-8 | | 2-4 |
| | | 3:00PM | vs. | Ohio Dominican College | L-3-14 | | 2-5 |
| March |
| | 1 | | @ | Georgetown College | W-2-1 | | 3-5 |
| | | 3:00PM | @ | Georgetown College | W-11-3 | | 4-5 |
| | 3 | 1:00PM | vs. | Taylor University | L-4-6 | | 4-6 |
| | 4 | 1:00PM | vs. | Taylor University | L-3-13 | | 4-7 |
| | 7 | | vs. | Goshen College | W-4-1 | | 5-7 |
| | | 1:00PM | vs. | Goshen College | L-3-12 | | 5-8 |
| | 11 | 12:00PM | vs. | Tri-State University | RAIN | | | |
| | | Game 2 | vs. | Tri-State University | RAIN | | | |
| * | 17 | 3:30PM | vs. | Berea | W-6-1 | | 6-8 1-0 |
| * | 18 | 12:00PM | vs. | Berea | L-1-2 | | 6-9 1-1 |
| * | | Game 2 | vs. | Berea | W-4-2 | | 7-9 2-1 |
| * | 24 | 2:00PM | @ | Bethel College | L-3-10 | | 7-10 2-2 |
| * | 25 | 12:00PM | @ | Bethel College | W-10-1 | | 8-10 3-2 |
| | Game 1 |
| * | | Game 2 | @ | Bethel College | W-7-0 | | 9-10 4-2 |
| | Game 2 |
| | 27 | | @ | Union University | W-19-12 | | 10-10 |
| | 28 | | @ | Freed-Hardeman | L-1-11 | | 10-11 |
| | | Game 2 | @ | Freed-Hardeman | L-5-6 | | 10-12 |
| * | 31 | 3:00PM | vs. | Spalding University | L-3-4 | | 10-13 4-3 |
| April |
| * | 1 | 1:00PM | vs. | Spalding University | W-7-6 | | 11-13 5-3 |
| * | | Game 2 | vs. | Spalding University | W-17-7 | | 12-13 6-3 |
| | 4 | | vs. | University of the Cumberlands | W-16-8 | | 13-13 |
| | 5 | 3:30PM | vs. | Oakland City University | L-5-6 | | 13-14 |
| | | Game 2 | vs. | Oakland City University | W-10-2 | | 14-14 |
| | 8 | 1:00PM | @ | Bethel College | L-3-4 | | 14-15 |
| | | 3:00PM | @ | Bethel College | L-1-11 | | 14-16 |
| | 9 | 3:00PM | @ | Lindsey Wilson | L-9-10 | | 14-17 |
| | 11 | 3:30PM | vs. | Hanover College | W-12-10 | | 15-17 |
| | 12 | 3:00PM | @ | Campbellsville University | L-6-9 | | 15-18 |
| * | 14 | 1:00PM | @ | Alice Lloyd | W-11-3 | | 16-18 7-3 |
| * | 15 | 1:00PM | @ | Alice Lloyd | L-2-5 | | 16-19 7-4 |
| * | | Game 2 | @ | Alice Lloyd | W-7-2 | | 17-19 8-4 |
| * | 22 | 12:00PM | vs. | Brescia | L-1-2 | | 17-20 8-5 |
| * | | 2:00PM | vs. | Brescia | W-7-6 | | 18-20 9-5 |
| * | 23 | 12:00PM | vs. | Brescia | W-14-4 | | 19-20 10-5 |
| | 27 | 1:00PM | vs. | Hanover College | W-5-4 | | 20-20 |
| | | Game 2 | vs. | Hanover College | L-1-10 | | 20-21 |
| * | 28 | 3:00PM | @ | Mid-Continent College | W-17-7 | | 21-21 11-5 |
| * | 29 | 12:00PM | @ | Mid-Continent College | W-8-5 | | 22-21 12-5 |
| * | | Game 2 | @ | Mid-Continent College | W-9-5 | | 23-21 13-5 |
| | Game 2 |
| May |
| | 3 | 2:30PM | vs. | Berea | W-9-2 | | 24-21 |
| | KIAC Tournament Day One |
| | 4 | 2:30PM | vs. | Alice Lloyd | W-4-3 | | 25-21 |
| | KIAC Tournament Day Two |
| | 5 | 3:00PM | vs. | Spalding University | L-3-4 | | 25-22 |
| | KIAC Tournament Day Three |
| | | 7:00PM | vs. | Brescia | W-6-3 | | 26-22 |
| | KIAC Tournament Day Three |
| | 6 | 1:00PM | vs. | Spalding University | W-6-5 | | 27-22 |
| | KIAC Tournament Championship-Game One |
| | | 5:00PM | vs. | Spalding University | L-2-6 | | 27-23 |
| | KIAC Tournament Championship-Spalding Wins Tournament |
| | 10 | 3:00PM | vs. | Tennessee Wesleyan | L-7-12 | | 27-24 |
| | NAIA REGION XII TOURNEY |
| | 11 | 11:00AM | vs. | Brevard College | W-7-3 | | 28-24 |
| | NAIA REGION XII TOURNEY |
| | 12 | 3:00PM | vs. | Spalding University | L-5-6 | | 28-25 |
| | NAIA REGION XII TOURNEY |
