| | Day | Time | | Opponent | Score | | Record |
| October |
| * | 29 | 6:00PM | @ | Mid-Continent College | W-98-29 |  | 1-0 1-0 |
| | Coached by Lorenzo Duncan |
| November |
| | 5 | 3:00PM | vs. | King College | L-63-82 | | 1-0 1-1 |
| | 12 | 3:00PM | vs. | Virginia Intermont College | W-79-48 | | 1-0 2-1 |
| | 15 | 7:00PM | @ | Kentucky State University | L-64-77 | | 1-0 2-2 |
| | 18 | 2:00PM | vs. | Purdue University Calumet | W-74-48 | | 1-0 3-2 |
| | Innovative PT Classic @ Bethel College (TN) |
| | 19 | | vs. | Williams Baptist College | L-51-74 | | 1-0 3-3 |
| | Innovative PT Classic @ Bethel College (TN) |
| * | 29 | 7:00PM | @ | Alice Lloyd | L-65-74 | | 1-1 3-4 |
| | 30 | 8:00PM | vs. | SCAD | W-77-65 | | 1-1 4-4 |
| December |
| | 2 | 4:00PM | vs. | UVA-Wise | L-53-54 | | 1-1 4-5 |
| | 2nd Annual Shootout in Shenandoah Tournament @ So. VA University |
| | 3 | 3:00PM | @ | Southern Virginia University | L-64-66 | | 1-1 4-6 |
| | 2nd Annual Shootout in Shenandoah Tournament @ So. VA University |
| * | 6 | 8:00PM | vs. | Mid-Continent College | W-80-41 | | 2-1 5-6 |
| | 10 | 5:00PM | vs. | Taylor University-Ft. Wayne | W-69-58 | | 2-1 6-6 |
| | 17 | 1:00PM | @ | Virginia Intermont College | L-55-69 | | 2-1 6-7 |
| January |
| | 5 | 8:00PM | vs. | Oakland City University | L-56-69 | | 2-1 6-8 |
| | 7 | 5:00PM | @ | Taylor University-Ft. Wayne | L-65-69 | | 2-1 6-9 |
| | 9 | 6:00PM | vs. | St. Mary of the Woods | W-72-47 | | 2-1 7-9 |
| * | 12 | 7:00PM | vs. | Berea | L-78-109 | | 2-2 7-10 |
| | Berea College is Ranked #28 in NAIA Division II |
| * | 14 | 3:00PM | vs. | SLCOP | W-73-36 | | 3-2 8-10 |
| * | 17 | 10:00PM | @ | Spalding University | L-57-60 | | 3-3 8-11 |
| | Ashley Parker (So. - Midway, FL) collected her 500th Career Rebound in just her 38th career game. |
| * | 19 | 7:30PM | @ | IU Southeast | W-63-55 | | 4-3 9-11 |
| * | 21 | 2:00PM | vs. | Bethel College | L-56-75 | | 4-4 9-12 |
| | Bethel College (TN) is Ranked #17 in NAIA Division II |
| * | 28 | 2:00PM | vs. | Spalding University | W-58-56 | | 5-4 10-12 |
| * | 31 | 8:00PM | vs. | Alice Lloyd | W-84-67 | | 6-4 11-12 |
| | Natalie Dial (Sr. - Russell, KY) scored her 1,500 career point. |
| February |
| * | 2 | 7:00PM | vs. | Asbury | W-78-55 | | 7-4 12-12 |
| | 4 | 2:00PM | @ | Kentucky Christian College | L-58-68 | | 7-4 12-13 |
| | KCU is the #1 Ranked Team in NCCAA II. |
| * | 7 | 8:00PM | @ | Berea | L-88-113 | | 7-5 12-14 |
| * | 9 | 7:00PM | vs. | IU Southeast | W-62-61 | | 8-5 13-14 |
| | Amy Klein's ('99-'03) Jersey Retirement Ceremony at Half-time. |
| * | 11 | 3:00PM | @ | Bethel College | L-71-94 | | 8-6 13-15 |
| * | 16 | 7:00PM | @ | Asbury | W-63-62 | | 9-6 14-15 |
| | Tia Garrett (SR. - Georgetown, KY) scored her 1,000th Career Point. She becomes just the 7th player in Midway College Basketball History to score over 1,000 points for her career. |
| | 18 | 2:00PM | @ | St. Mary of the Woods | W-73-45 | | 9-6 15-15 |
| | 20 | 7:00PM | vs. | Kentucky Christian College | W-66-64 | | 9-6 16-15 |
| | Senior Night honoring Tia Garrett and Natalie Dial. Dial became the All-Time Leading Scorer at Midway College tonight. She currently has 1,645 career points. Garrett moved into 5th place All-Time in scoring with 1,044 career points. Midway College Basketball finished the season 16-15, the first winning season since 1995-96. |
| | 22 | 8:00PM | vs. | Spalding University | W-81-69 | | 9-6 17-15 |
| | First Round of KIAC Tournament #3 - Midway College versus #6 - Spalding University |
| | 24 | 2:00PM | vs. | Bethel College | L-73-78 | | 9-6 17-16 |
| | Semifinal #1 of KIAC Women's Basketball Tournament |
