| October |
| * | 29 | 6:00PM | Midway | @ | Mid-Continent College | 98-29 |  |
| | Coached by Lorenzo Duncan |
| November |
| | 1 | 7:30PM | Kentucky Christian College | @ | Alice Lloyd | 77-67 | |
| | Belicia Mullins joins 1,000 piont club for alc |
| | | 9:00PM | Blue Mountain College | @ | Mid-Continent College | 95-50 | |
| | | 9:00PM | SLCOP | @ | Missouri Baptist College | 32-79 | |
| | 4 | 2:00PM | IU Southeast | @ | St. Mary's | 57-39 | |
| | | 4:00PM | IU Southeast | @ | St. Mary of the Woods | 57-39 | |
| | IU Southeast is now 1-0 (0-0 KAIC) - FWO/Courtyard Marriott - First Round |
| | | 6:00PM | Spalding University | @ | Freed-Hardeman | 50-103 | |
| | 5 | | Spalding University | vs. | Cumberland Univ. | 41-100 | |
| | | 5:00AM | SLCOP | @ | Hannibal-LaGrange College | 46-76 | |
| | | 3:00PM | King College | @ | Midway | 82-63 | |
| | | 6:00PM | Covenant College | @ | Bethel College | 76-77 | |
| | Seat hits game winner with 1 second left |
| | | 6:00PM | IU Southeast | @ | University of Saint Francis | 60-91 | |
| | FWO/Courtyard Marriott Championship Game |
| | | 6:30PM | UVA-Wise | @ | Berea | 103-88 | |
| | 8 | 6:00PM | Philander Smith College | @ | Bethel College | 53-83 | |
| | | 7:30PM | St. Andrews College | @ | IU Southeast | 80-78 | (OT) |
| | IU Southeast is now 1-2 (0-0 KIAC) this season. |
| | | 7:30PM | St. Louis Christian | @ | SLCOP | 20-85 | |
| | | 9:30PM | Alice Lloyd | vs. | Bluefield College | 103-78 | |
| | wendy's classic |
| | 10 | 9:00PM | Asbury | vs. | Southeastern College | 63-65 | |
| | Kentucky Christian University-Super 8 Classic |
| | 11 | 6:00PM | Spalding University | @ | King College | 56-83 | |
| | | 7:00PM | William Carey College | @ | Bethel College | 58-73 | |
| | | 8:00PM | SLCOP | @ | Baptist Bible College | 49-51 | |
| | | 9:00PM | Asbury | vs. | Toccoa Falls College | 67-56 | |
| | Kentucky Christian University-Super 8 Classic |
| | | 9:00PM | Berea | @ | Olivet Nazarene University | 72-112 | |
| | 12 | | SLCOP | @ | Central Babtist College | 60-81 | |
| | Baptist Bible Tourney 11/11-12 |
| | | 3:00PM | Virginia Intermont College | @ | Midway | 48-79 | |
| * | | 4:00PM | IU Southeast | @ | Mid-Continent College | 71-36 | |
| | Coach Kevin Brown |
| | | 5:00PM | Asbury | vs. | Atlanta Christian | 62-51 | |
| | Kentucky Christian University-Super 8 Classic |
| | | 5:00PM | Bethel College | vs. | Berea | 89-95 | |
| | Olivet Nazarene Tournament |
| | | 8:00PM | Point Park College | vs. | Alice Lloyd | 66-77 | |
| | Wendy's Classic |
| | 14 | 7:00PM | Pikeville College | @ | Spalding University | 53-58 | |
| | 15 | 6:00PM | Brescia | @ | Southern Indiana | 62-87 | |
| | | 7:00PM | IU Southeast | @ | Oakland City University | 55-59 | |
| | Make-up game for originally scheduled game 11/15/05 |
| | | 7:00PM | Midway | @ | Kentucky State University | 64-77 | |
| | | 8:00PM | Berea | @ | Knoxville College | 127-69 | |
| | | 10:00PM | Asbury | @ | Cincinnati Christian | 67-49 | |
| | 16 | 7:00PM | Harris-Stowe State College | @ | SLCOP | 62-69 | |
| | 17 | 6:00PM | Spalding University | @ | Lindsey Wilson | 39-71 | |
| | | 10:00PM | Temple Baptist College | @ | Asbury | 40-65 | |
| | 18 | 2:00PM | Midway | vs. | Purdue University Calumet | 74-48 | |
| | Innovative PT Classic @ Bethel College (TN) |
| | | 6:00PM | SLCOP | @ | Maryville University-St. Louis | 35-102 | |
| | Maryville Tip-Off 11/18-19 |
| | | 6:00PM | Williams Baptist College | @ | Bethel College | 60-66 | (OT) |
| | Innovative PT Classic @ Bethel (Tenn.) |
| | | 6:00PM | IU Southeast | vs. | Transylvania University | 62-50 | |
| | | 6:00PM | Brescia | vs. | Pikeville College | 63-74 | |
| | 19 | | SLCOP | vs. | Lincoln Christian College | 50-65 | |
| | Maryville Tip-Off 11/18-19 |
| | | | Midway | vs. | Williams Baptist College | 51-74 | |
| | Innovative PT Classic @ Bethel College (TN) |
| | | | Martin Methodist | @ | Spalding University | 79-62 | |
| | | 4:00PM | IU Southeast | vs. | University of the South | 49-77 | |
| * | | 6:00PM | Berea | @ | Mid-Continent College | 127-68 | |
| | | 6:00PM | Purdue University Calumet | @ | Bethel College | 65-73 | |
| | Innovative PT Classic at Bethel College (Tenn.) |
| | | 6:00PM | Alice Lloyd | vs. | Appalachian Bible College | 78-28 | |
| | | 6:00PM | Brescia | vs. | University of the Cumberlands | 36-68 | |
| | 21 | 8:00PM | Mid-Continent College | @ | Blue Mountain College | 30-91 | |
| | 22 | 7:00PM | Brescia | @ | Franklin College | 57-80 | |
| | | 7:30PM | Union College | vs. | Alice Lloyd | 74-65 | |
| * | | 8:00PM | Asbury | @ | Bethel College | 53-98 | |
| | | 8:00PM | Temple Baptist College | @ | Berea | 77-127 | |
| | | 9:00PM | SLCOP | @ | Greenville College | 39-63 | |
| | | 10:00PM | Spalding University | @ | St. Mary of the Woods | 70-56 | |
| | 26 | 2:00PM | Brescia | @ | Kentucky Wesleyan College | 63-93 | |
| * | 28 | 9:00PM | Mid-Continent College | @ | Bethel College | 29-104 | |
| | 29 | 5:00PM | Principia College | @ | SLCOP | 75-78 | |
| | | 6:00PM | Bethel College | @ | Lambuth University | 86-98 | |
| | | 6:00PM | Brescia | @ | Freed-Hardeman | 42-95 | |
| | | 6:30PM | SCAD | @ | Berea | 73-95 | |
| * | | 7:00PM | Midway | @ | Alice Lloyd | 65-74 | |
| | | 7:30PM | Transylvania University | @ | IU Southeast | 50-64 | |
| | | 10:00PM | Cincinnati Christian | @ | Spalding University | 39-85 | |
| | Exh. Game |
| | 30 | 8:00PM | SCAD | @ | Midway | 65-77 | |
| December |
| | 1 | 8:00PM | Transylvania University | @ | Asbury | 83-73 | |
| | | 9:30PM | Spalding University | @ | Trinity Christian College | 66-79 | |
| | 2 | 4:00PM | Midway | vs. | UVA-Wise | 53-54 | |
| | 2nd Annual Shootout in Shenandoah Tournament @ So. VA University |
| | | 6:00PM | Central Babtist College | @ | Bethel College | 66-99 | |
| | | 7:00PM | Brescia | vs. | Pikeville College | 62-46 | |
| | | 8:00PM | Mid-Continent College | @ | St. Louis Christian | 86-40 | |
| | 3 | | SLCOP | vs. | Alice Lloyd | 54-87 | |
| | | 1:00PM | Central Babtist College | vs. | IU Southeast | 62-77 | |
| | Bethel College (Tenn.) Classic |
| | | 3:00PM | Midway | @ | Southern Virginia University | 64-66 | |
| | 2nd Annual Shootout in Shenandoah Tournament @ So. VA University |
| | | 3:00PM | Brescia | @ | University of the Cumberlands | 56-61 | |
| | | 6:00PM | McKendree College | @ | Bethel College | 63-79 | |
| | McKenzie Rotary Club Classic @ Bethel (Tenn.) |
| * | | 7:00PM | Alice Lloyd | @ | SLCOP | 87-54 | |
| | 5 | 7:00PM | Appalachian Bible College | vs. | Alice Lloyd | 25-90 | |
| | 6 | 7:00PM | Brescia | @ | Georgetown College | 58-88 | |
| * | | 8:00PM | Mid-Continent College | @ | Midway | 41-80 | |
| | | 10:00PM | Kentucky Christian College | @ | Asbury | 76-50 | |
| | | 10:00PM | Franklin College | @ | Spalding University | 65-50 | |
| | 8 | 5:30PM | Alice Lloyd | @ | Kentucky Christian College | 67-78 | |
| | | 8:00PM | Knoxville College | @ | Berea | 58-127 | |
| | 9 | 5:00PM | Brescia | vs. | Cumberland Univ. | 69-98 | |
| | | 7:00PM | Taylor University-Ft. Wayne | @ | IU Southeast | 49-69 | |
| | | 7:30PM | Baptist Bible College | @ | SLCOP | 60-42 | |
| | | 10:00PM | Johnson Bible College | @ | Asbury | 34-83 | |
| * | 10 | 12:00PM | Bethel College | @ | Alice Lloyd | 80-67 | |
| | | 2:00PM | Brescia | @ | Trevecca Nazarene University | 42-97 | |
| | | 3:00PM | St. Mary of the Woods | @ | Asbury | 67-76 | |
| | | 5:00PM | Taylor University-Ft. Wayne | @ | Midway | 58-69 | |
| * | | 6:00PM | SLCOP | @ | Mid-Continent College | 68-43 | |
| | 13 | 7:00PM | St. Mary of the Woods | @ | IU Southeast | 46-69 | |
| | | 8:00PM | Spalding University | @ | Goshen College | 51-50 | |
| | 14 | 1:00PM | King College | @ | Berea | 86-96 | |
| | 15 | 7:00PM | Union College | @ | Spalding University | 63-65 | |
| | 16 | 5:00PM | Purdue University Calumet | vs. | Bethel College | 67-63 | |
| | | 6:00PM | Brescia | vs. | Lindsey Wilson | 53-71 | |
| | | 7:00PM | Berea | vs. | Ohio Northern | 98-99 | |
| | 17 | 1:00PM | Midway | @ | Virginia Intermont College | 55-69 | |
| | | 1:00PM | Brescia | @ | Campbellsville University | 49-59 | |
| | | 2:00PM | Berea | @ | Defiance College | 96-102 | (OT) |
| | Defiance College Tournament |
| * | | 3:00PM | IU Southeast | @ | Alice Lloyd | 76-67 | |
| | | 5:00PM | Bethel College | @ | Trinity Christian College | 75-80 | |
| | TCC Classic |
| * | | 7:00PM | Spalding University | @ | Mid-Continent College | 90-59 | |
| | 20 | 6:30PM | Alice Lloyd | vs. | Virginia Intermont College | 98-99 | (2OT) |
| | 29 | 6:00PM | Brescia | @ | Northern Kentucky | 42-63 | |
| | | 8:00PM | Union College | vs. | Berea | 80-84 | |
| | King College tournament |
| | 30 | | Lambuth University | @ | Spalding University | 62-50 | |
| | v. Lambuth University |
| | | 2:00PM | Berea | @ | King College | 96-79 | |
| January |
| | 2 | 6:30PM | Virginia Intermont College | @ | Berea | 69-97 | |
| | 3 | 7:30PM | Spalding University | @ | Union College | 53-56 | |
| | 4 | 9:00PM | Bethel College | @ | Brescia | 59-54 | |
| | 5 | 8:00PM | Oakland City University | @ | Midway | 69-56 | |
| | 6 | | Brescia | @ | Lambuth University | 49-71 | |
| * | 7 | 1:00PM | Berea | @ | Bethel College | 83-101 | |
| | | 4:00PM | Ohio Christian | vs. | Alice Lloyd | 28-103 | |
| * | | 5:00PM | Asbury | @ | Mid-Continent College | 80-53 | |
| | | 5:00PM | Midway | @ | Taylor University-Ft. Wayne | 65-69 | |
| * | | 6:00PM | IU Southeast | @ | Spalding University | 49-59 | |
| | | 6:00PM | Brescia | vs. | Union University | 62-97 | |
| | 9 | 6:00PM | St. Mary of the Woods | @ | Midway | 47-72 | |
| * | 10 | 6:00PM | Alice Lloyd | @ | Bethel College | 59-99 | |
| | | 6:00PM | Brescia | @ | Oakland City University | 64-85 | |
| * | | 8:30PM | Asbury | @ | IU Southeast | 52-75 | |
| | 12 | 5:30PM | Alice Lloyd | vs. | Union College | 61-71 | |
| | | 6:00PM | Asbury | @ | Johnson Bible College | 70-48 | |
| * | | 7:00PM | Berea | @ | Midway | 109-78 | |
| | Berea College is Ranked #28 in NAIA Division II |
| | | 7:00PM | IU Southeast | @ | St. Mary of the Woods | 77-46 | |
| | 13 | 8:00PM | Asbury | @ | Taylor University-Ft. Wayne | 65-63 | |
| * | 14 | 1:00PM | Spalding University | @ | Bethel College | 49-79 | |
| * | | 3:00PM | SLCOP | @ | Midway | 36-73 | |
| | | 4:30PM | Pikeville College | vs. | Alice Lloyd | 78-75 | |
| | Pikeville won on last second shot |
| * | | 5:00PM | Berea | @ | IU Southeast | 97-85 | |
| | 15 | 3:00PM | University of the Cumberlands | @ | Brescia | 64-45 | |
| | 16 | 7:00PM | Alice Lloyd | vs. | Free Will Baptist | 74-47 | |
| | | 9:00PM | University of Illinois at Springfield | @ | Bethel College | 50-82 | |
| | 17 | 4:30PM | Brescia | @ | Georgetown College | 44-79 | |
| | | 7:30PM | Alice Lloyd | vs. | Cincinnati Christian | 84-50 | |
| * | | 8:00PM | IU Southeast | @ | Asbury | 64-57 | |
| * | | 10:00PM | Midway | @ | Spalding University | 57-60 | |
| | Ashley Parker (So. - Midway, FL) collected her 500th Career Rebound in just her 38th career game. |
| * | 19 | 7:00PM | Bethel College | @ | Asbury | 84-45 | |
| * | | 7:30PM | Midway | @ | IU Southeast | 63-55 | |
| * | 21 | 1:00PM | Berea | @ | Asbury | 90-68 | |
| | | 1:00PM | IU Southeast | @ | Kentucky Christian College | 57-77 | |
| * | | 2:00PM | Bethel College | @ | Midway | 75-56 | |
| | Bethel College (TN) is Ranked #17 in NAIA Division II |
| * | | 2:00PM | Alice Lloyd | @ | Spalding University | 81-84 | |
| | 23 | 9:00PM | McMurray College | @ | SLCOP | 75-61 | |
| * | 24 | 6:00PM | Asbury | @ | Alice Lloyd | 60-63 | |
| * | | 6:30PM | Spalding University | @ | Berea | 83-97 | |
| | | 6:30PM | Mid-Continent College | @ | St. Andrews College | 43-76 | |
| | | 7:00PM | Brescia | @ | Cumberland Univ. | 56-76 | |
| * | 26 | 6:00PM | Berea | @ | Alice Lloyd | 104-98 | |
| | | 7:00PM | Brescia | @ | McKendree College | 52-62 | |
| | | 7:00PM | Asbury | @ | Kentucky Christian College | 47-59 | |
| | | 7:30PM | Bethel College | @ | Philander Smith College | 82-58 | |
| | | 8:00PM | Stephens College | @ | SLCOP | 63-56 | |
| | 27 | 7:00PM | Mid-Continent College | @ | Johnson Bible College | 80-54 | |
| | 28 | 2:00PM | Asbury | @ | St. Mary of the Woods | 73-89 | |
| * | | 2:00PM | SLCOP | @ | Berea | 67-116 | |
| * | | 2:00PM | Spalding University | @ | Midway | 56-58 | |
| * | | 2:00PM | IU Southeast | @ | Bethel College | 66-67 | |
| | 30 | 7:00PM | Mid-Continent College | @ | Oakwood College | 50-56 | |
| | Oakwood requests date change from 2/13 |
| * | 31 | 7:00PM | Spalding University | @ | Asbury | 48-51 | |
| * | | 8:00PM | Alice Lloyd | @ | Midway | 67-84 | |
| | Natalie Dial (Sr. - Russell, KY) scored her 1,500 career point. |
| | | 8:00PM | Lambuth University | @ | Bethel College | 56-73 | |
| February |
| | 1 | 7:00PM | SLCOP | @ | Eureka College | 49-64 | |
| | 2 | 6:00PM | Trevecca Nazarene University | @ | Brescia | 64-57 | |
| * | | 6:30PM | Alice Lloyd | @ | Berea | 98-114 | |
| | Sr. Guard Crystal Davis, Wilmington, OH gets her 500th assist tonight. |
| * | | 7:00PM | Asbury | @ | Midway | 55-78 | |
| * | | 7:00PM | Spalding University | @ | IU Southeast | 50-64 | |
| * | | 7:00PM | Mid-Continent College | @ | Bethel College | 47-88 | |
| | Bethel wins 11th straight and 21st game of season |
| * | 4 | 2:00PM | SLCOP | @ | Asbury | 45-80 | |
| | | 2:00PM | Midway | @ | Kentucky Christian College | 58-68 | |
| | KCU is the #1 Ranked Team in NCCAA II. |
| | | 2:00PM | Cumberland Univ. | @ | Brescia | 87-61 | |
| * | | 3:00PM | Bethel College | @ | Spalding University | 78-74 | |
| * | | 4:00PM | Alice Lloyd | @ | Mid-Continent College | 85-60 | |
| * | | 6:00PM | IU Southeast | @ | Berea | 79-80 | |
| * | 6 | 7:00PM | Mid-Continent College | @ | Spalding University | 41-73 | |
| * | 7 | 5:00PM | Bethel College | @ | SLCOP | 94-42 | |
| | | 5:30PM | UVA-Wise | @ | Alice Lloyd | 79-55 | |
| * | | 5:30PM | Mid-Continent College | @ | IU Southeast | 33-91 | |
| * | | 7:00PM | Asbury | @ | Spalding University | 65-55 | |
| | | 7:00PM | Campbellsville University | @ | Brescia | 61-52 | |
| * | | 8:00PM | Midway | @ | Berea | 88-113 | |
| | 8 | 7:00PM | Oakland City University | @ | Brescia | 69-58 | |
| * | 9 | 6:00PM | Asbury | @ | Berea | 62-106 | |
| * | | 7:00PM | IU Southeast | @ | Midway | 61-62 | |
| | Amy Klein's ('99-'03) Jersey Retirement Ceremony at Half-time. |
| | | 7:00PM | SLCOP | @ | Principia College | 45-74 | |
| * | 10 | 7:00PM | Mid-Continent College | @ | Berea | 53-114 | |
| | 11 | 12:00PM | Brescia | @ | Park University | 60-87 | |
| * | | 2:00PM | Spalding University | @ | SLCOP | 82-44 | |
| * | | 3:00PM | Alice Lloyd | @ | IU Southeast | 58-90 | |
| * | | 3:00PM | Midway | @ | Bethel College | 71-94 | |
| * | | 4:00PM | Mid-Continent College | @ | Asbury | 64-86 | |
| | 13 | 8:00PM | SLCOP | @ | Stephens College | 38-73 | |
| * | 14 | 6:00PM | Alice Lloyd | @ | Asbury | 101-74 | |
| * | | 8:00PM | Berea | @ | Spalding University | 86-73 | |
| | At Berea College |
| * | 16 | 7:00PM | Midway | @ | Asbury | 63-62 | |
| | Tia Garrett (SR. - Georgetown, KY) scored her 1,000th Career Point. She becomes just the 7th player in Midway College Basketball History to score over 1,000 points for her career. |
| * | | 7:30PM | Bethel College | @ | IU Southeast | 89-77 | |
| | Bethel wins 15th straight and improves to 14-0 in conference action |
| * | 17 | 6:00PM | Mid-Continent College | @ | Alice Lloyd | 38-85 | |
| | 18 | 2:00PM | Taylor University-Ft. Wayne | @ | Asbury | 53-70 | |
| | Asbury's 14th win on the season, setting a school-record for wins in a given season. |
| | | 2:00PM | Brescia | @ | Union University | 61-112 | |
| | | 2:00PM | Midway | @ | St. Mary of the Woods | 73-45 | |