| October |
| | 28 | 8:00PM | IU Southeast | @ | Calumet College of St. Joseph | 76-64 |  |
| | Maple City Hoopfest |
| | 29 | 2:00PM | IU Southeast | @ | Goshen College | 84-73 |  |
| | Maple City Hoopfest |
| | | 10:00PM | ABAC | vs. | Mid-Continent College | 61-82 | |
| | Heritage Baptist University |
| November |
| | 1 | | SLCOP | @ | St. Louis Christian | 57-60 | (OT) |
| | | 7:00PM | Bethel College | @ | Free Will Baptist | 62-53 | |
| | | 7:00PM | Spalding University | @ | Georgetown College | 56-93 | |
| | | 8:30PM | Kentucky Christian College | @ | Alice Lloyd | 94-121 |  |
| | | 9:00PM | Temple Baptist College | @ | Asbury | 61-85 | |
| | 3 | 11:00PM | Mid-Continent College | vs. | Alice Lloyd | 76-113 |  |
| | Kentucky Christian University Classic |
| | 4 | | Mid-Continent College | @ | Kentucky Christian College | 104-116 | |
| | Kentucky Christian Tournament |
| | | 7:00PM | Shawnee State University | vs. | Alice Lloyd | 75-69 |  |
| | Kentucky Christian University Classic |
| % | 5 | 1:00PM | Mid-Continent College | vs. | Valley Forge Christian | 75-84 | |
| | Kentucky Christian Tournament |
| | | 3:00PM | Asbury | @ | Johnson Bible College | 91-94 | |
| | | 3:00PM | Purdue University-North Central | @ | IU Southeast | 55-63 |  |
| | | 3:00PM | Lambuth University | vs. | Alice Lloyd | 92-85 |  |
| | Kentucky Christian University Classic |
| | | 4:00PM | Spalding University | @ | Lindsey Wilson | 59-72 | |
| | | 6:00PM | Wesley College | @ | Bethel College | 59-79 |  |
| | | 8:30PM | Milligan College | @ | Berea | 68-76 | |
| % | 7 | 7:00PM | Bethel College | @ | Tennessee-Martin | 69-89 | |
| | Exhibition |
| | 8 | | Asbury | @ | Cincinnati Christian | 89-74 | |
| | | 9:00PM | Lindenwood University | @ | SLCOP | 80-59 | |
| | | 9:00PM | Spalding University | @ | University of the Cumberlands | 60-71 |  |
| | | 10:00PM | Spalding University | @ | Cumberland Univ. | 60-71 | |
| | | 10:30PM | Alice Lloyd | @ | UVA-Wise | 72-75 |  |
| % | 9 | 8:00PM | Asbury | @ | Morehead State | 82-85 | |
| | 10 | 10:00PM | Campbellsville University | @ | Spalding University | 76-69 |  |
| | 11 | | SLCOP | vs. | Williams Baptist College | 70-83 | |
| | | 5:00PM | Brescia | vs. | Cumberland Univ. | 75-71 | |
| | | 6:00PM | Virginia Intermont College | vs. | Bethel College | 76-79 | |
| | Lambuth University (Tenn.) Classic |
| | | 7:30PM | Bethel College | vs. | Temple Baptist College | 65-63 |  |
| | Lambuth University (Tenn.) Classic |
| | | 9:00PM | Reinhardt College | @ | Berea | 100-79 | |
| | | 11:00PM | Ohio Southern | @ | Asbury | 71-109 | |
| | Zweifel Tournament |
| | 12 | | Grace College | @ | Asbury | 100-78 | |
| | Asbury Tournament - Nov. 11-12 |
| | | 4:00PM | King College | @ | Berea | 75-68 | (OT) |
| | | 5:00PM | Brescia | vs. | Olivet Nazarene University | 77-68 | |
| * | | 6:00PM | IU Southeast | @ | Mid-Continent College | 92-69 |  |
| | 14 | 6:00PM | Spalding University | @ | Pikeville College | 58-53 |  |
| | | 9:00PM | Logan Chiropractic | @ | SLCOP | 78-90 | |
| | | 9:00PM | Alice Lloyd | @ | Ohio Christian | 101-50 | |
| | 15 | 7:00PM | Harris-Stowe State College | @ | Bethel College | 66-68 |  |
| | | 8:30PM | Asbury | @ | Temple Baptist College | 97-79 | |
| | | 8:30PM | Crown College | @ | Berea | 64-93 | |
| | 18 | 8:00PM | Mid-Continent College | @ | Bethel College | 68-81 | |
| | Bethel Men's Tournament |
| | | 10:30PM | Centre College | @ | Asbury | 79-67 | |
| | 19 | 12:00PM | Mid-Continent College | vs. | Williams Baptist College | 59-124 | |
| | Innovative PT Classic at Bethel College (Tenn.) |
| | | 2:00PM | Crossroads College | @ | Bethel College | 78-104 |  |
| | Innovative PT Classic |
| | | 5:00PM | University of Dubuque | @ | SLCOP | 88-57 | |
| * | | 8:00PM | Berea | @ | Mid-Continent College | 117-74 | |
| | | 8:00PM | Spalding University | @ | Brescia | 58-69 | |
| * | 22 | 7:00PM | Bethel College | @ | SLCOP | 83-62 |  |
| | | 7:00PM | IU Southeast | @ | Brescia | 64-62 |  |
| | | 8:00PM | Asbury | @ | Charleston Southern University | 61-108 | |
| | | 9:30PM | Union College | @ | Alice Lloyd | 99-85 |  |
| | 23 | 7:00PM | Berea | @ | King College | 65-74 |  |
| | | 8:15PM | Asbury | @ | The Citadel | 48-75 | |
| | 25 | 6:00PM | Brescia | vs. | University of Missouri-Rolla | 57-70 | |
| | | 10:00PM | Mid-Continent College | @ | Oakland City University | 63-116 | |
| | Quality Inn Classic |
| | 26 | | Brescia | vs. | Lincoln University | 76-65 | |
| | | 3:00PM | Indiana University Northwest | @ | IU Southeast | 49-96 |  |
| % | | 8:30PM | Mid-Continent College | vs. | Oakland City University | 51-99 | |
| | HERITAGE Quality Inn Classic at Baptist Academy |
| | 29 | 7:00PM | Georgetown College | @ | Brescia | 88-55 | |
| | | 8:30PM | Pikeville College | @ | Alice Lloyd | 79-83 | (OT) |
| | | 9:00PM | Principia College | @ | SLCOP | 55-83 | |
| | | 10:30PM | Centre College | @ | Berea | 69-42 | |
| December |
| | 1 | 8:00PM | Asbury | @ | Tennessee-Chattanooga | 60-97 | |
| | | 9:00PM | SLCOP | @ | Greenville College | 75-72 | |
| | 2 | | Mid-Continent College | @ | St. Louis Christian | 73-88 | |
| | | 8:00PM | Florida College | @ | Bethel College | 75-76 |  |
| | McKenzie Rotary Club Classic at Bethel College |
| | | 8:30PM | Concordia University | vs. | Spalding University | 74-65 |  |
| | Food for the Hungry Holiday Invitational - First Round |
| * | 3 | | Alice Lloyd | vs. | SLCOP | 79-63 | |
| | | 2:00PM | Calumet College of St. Joseph | vs. | Spalding University | 62-57 | (OT) |
| | Food for the Hungry Holiday Invitational - Consolation Game |
| | | 2:00PM | University of Illinois at Springfield | @ | Brescia | 69-73 | |
| | | 3:00PM | Purdue University Calumet | @ | IU Southeast | 78-71 |  |
| | | 5:00PM | Crown College | @ | Asbury | 80-112 | |
| | | 6:00PM | Pikeville College | @ | Bethel College | 68-84 |  |
| | McKenzie Rotary Club Classic at Bethel College |
| | | 8:30PM | University of the Cumberlands | @ | Berea | 88-68 | |
| | | 11:00PM | Mid-Continent College | @ | Logan Chiropractic | 96-102 | |
| | 5 | 8:00PM | Spalding University | @ | Tennessee-Martin | 59-79 | |
| | | 8:00PM | Appalachian Bible College | @ | Alice Lloyd | 68-92 | |
| | 6 | | Brescia | @ | Campbellsville University | 67-72 | |
| | | | Asbury | @ | Free Will Baptist | 88-72 | |
| | | 9:30PM | IU Southeast | @ | Cincinnati Christian | 87-64 |  |
| | 8 | 10:30PM | Alice Lloyd | @ | Kentucky Christian College | 116-87 | |
| | 9 | 8:00PM | Asbury | @ | Ohio Christian | 115-84 | |
| | | 9:00PM | Baptist Bible College | @ | SLCOP | 73-70 | |
| | 10 | 3:00PM | Berea | @ | Pikeville College | 63-75 |  |
| | | 3:00PM | Davenport University | @ | IU Southeast | 50-62 |  |
| | | 3:00PM | Brescia | @ | University of the Cumberlands | 64-63 | |
| * | | 6:00PM | Bethel College | @ | Alice Lloyd | 72-83 | |
| * | | 8:00PM | SLCOP | @ | Mid-Continent College | 71-73 | |
| | 13 | 7:00PM | Bethel College | @ | Concordia Seminary-St. Louis | 96-59 |  |
| | 14 | 10:30PM | Pikeville College | @ | Spalding University | 48-49 | |
| | 16 | 8:00PM | Temple Baptist College | @ | Bethel College | 68-102 |  |
| | McDonald's Classic at Bethel College (Tenn.) |
| | | 8:00PM | Ohio Southern | @ | Berea | 67-89 | |
| | 17 | 2:00PM | McKendree College | @ | Brescia | 71-73 | |
| | | 3:00PM | University of Rio Grande | @ | Bethel College | 57-64 |  |
| | McDonald's Classic at Bethel College (Tenn.) |
| | | 3:00PM | Indiana University-South Bend | vs. | IU Southeast | 55-64 |  |
| | Played at Indianapolis, Ind. |
| * | | 7:00PM | Spalding University | @ | Mid-Continent College | 90-59 | |
| | 18 | 3:00PM | IU Southeast | @ | Marian College | 66-59 | |
| | 21 | 7:00PM | IU Southeast | @ | Purdue University Calumet | 66-51 |  |
| | | 9:00PM | Alice Lloyd | @ | Warner Southern | 78-97 | |
| | 22 | 5:00PM | Alice Lloyd | vs. | Iowa Wesleyan College | 87-101 | |
| | Warner Southern Classic |
| | | 6:00PM | IU Southeast | @ | Indiana University Northwest | 79-72 |  |
| | 29 | 6:00PM | Berea | vs. | Hanover College | 63-70 | |
| | | 7:30PM | Indiana Wesleyan University | @ | IU Southeast | 72-88 |  |
| | | 9:00PM | Harris-Stowe State College | @ | Spalding University | 72-79 | |
| | 30 | | Berea | vs. | Emory & Henry College | 114-127 | |
| | Centre College Invitational |
| | | | Central Methodist College | vs. | Brescia | 55-59 | |
| | Coaches vs Cancer Classic - Columbia College |
| | 31 | 8:00PM | Brescia | @ | Columbia College | 60-71 | |
| January |
| | 2 | 8:30PM | Berea | @ | Milligan College | 79-89 | |
| | 3 | | Campbellsville University | vs. | Spalding University | 67-40 | |
| | At Gallatin County High SChool |
| | 4 | 3:00PM | IU Southeast | @ | Purdue University-North Central | 104-57 |  |
| | | 6:30PM | Bethel College | @ | Pikeville College | 49-75 |  |
| | 5 | 7:00PM | Brescia | @ | Martin Methodist | 56-61 | |
| | | 10:00PM | Illinois Institute of Technology | @ | Spalding University | 43-69 | |
| | 6 | | Ohio Southern | @ | Alice Lloyd | 59-96 | |
| * | 7 | | Asbury | @ | Mid-Continent College | 75-73 | |
| | Scoring error during game...2nd half, second FT not credited to M. Spann #5 |
| | | 2:00PM | Georgetown College | @ | IU Southeast | 71-74 | (OT) |
| | | 2:00PM | University of the Cumberlands | @ | Brescia | 71-50 | |
| * | | 3:00PM | Berea | @ | Bethel College | 67-65 |  |
| | | 5:00PM | Ohio Christian | @ | Alice Lloyd | 58-109 | |
| | 9 | 7:30PM | University of Illinois at Springfield | @ | IU Southeast | 60-76 | |
| | 10 | 7:00PM | Campbellsville University | @ | Brescia | 63-55 | |
| * | | 8:00PM | Alice Lloyd | @ | Bethel College | 72-78 |  |
| * | 11 | 10:30PM | Asbury | @ | Spalding University | 70-68 | |
| | 12 | 7:00PM | SLCOP | @ | Bethel College | 61-64 |  |
| | | 7:30PM | Brescia | @ | IU Southeast | 70-67 | (2OT) |
| | | 9:30PM | Alice Lloyd | @ | Union College | 83-88 |  |
| | | 10:00PM | Georgetown College | @ | Asbury | 96-58 | |
| | Rescheduled from Dec. 8, 2005 |
| * | 14 | 2:00PM | IU Southeast | @ | SLCOP | 70-59 |  |
| | | 2:00PM | Park University | @ | Brescia | 47-60 | |
| * | | 3:00PM | Spalding University | @ | Bethel College | 110-107 |  |
| * | | 4:00PM | Berea | @ | Alice Lloyd | 78-83 | |
| | | 7:00PM | Asbury | @ | IU East | 80-73 | |
| | 16 | 4:00PM | Mid-Continent College | @ | Crichton College | 54-109 |  |
| | | 4:00PM | Bethel College | @ | Harris-Stowe State College | 84-101 |  |
| | | 6:00PM | Alice Lloyd | @ | Pikeville College | 74-81 |  |
| | | 7:00PM | Martin Methodist | @ | Brescia | 44-69 | |
| * | 17 | 8:30PM | Asbury | @ | Berea | 74-96 | |
| * | 18 | 6:30PM | IU Southeast | @ | Spalding University | 77-52 |  |
| | 19 | 7:00PM | Brescia | @ | Lindsey Wilson | 64-61 |  |
| | 21 | 1:00PM | Brescia | vs. | Olivet Nazarene University | 58-69 | |
| * | | 3:00PM | Bethel College | @ | Asbury | 79-76 |  |
| | | 3:00PM | St. Louis Christian | @ | SLCOP | 67-69 | |
| * | | 4:00PM | Berea | @ | IU Southeast | 72-88 |  |
| * | | 4:00PM | Alice Lloyd | @ | Spalding University | 69-78 | |
| * | 24 | 7:00PM | Bethel College | @ | IU Southeast | 83-105 | |
| | | 7:00PM | Brescia | @ | Cumberland Univ. | 70-58 | |
| * | | 7:30PM | Spalding University | @ | Berea | 49-53 | |
| * | | 8:00PM | Asbury | @ | Alice Lloyd | 79-95 | |
| * | 26 | 7:30PM | Asbury | @ | IU Southeast | 96-102 |  |
| | 27 | 8:00PM | Logan Chiropractic | @ | SLCOP | 84-73 | |
| | StLCoP Tourney 1/27 & 1/28 |
| | | 10:00PM | Mid-Continent College | @ | Johnson Bible College | 82-101 | |
| | 28 | 2:00PM | Concordia Seminary-St. Louis | @ | SLCOP | 77-69 | |
| | StLCoP Tourney - 1/27 & 1/28 |
| | | 2:00PM | Berea | @ | Ohio Southern | 75-73 | |
| | | 3:00PM | Brescia | @ | Asbury | 55-59 | |
| * | | 4:00PM | IU Southeast | @ | Alice Lloyd | 88-78 |  |
| * | | 7:00PM | Bethel College | @ | Mid-Continent College | 79-68 |  |
| | 31 | 7:00PM | SLCOP | @ | Concordia Seminary-St. Louis | 62-75 | |
| | | 7:30PM | Bryan College | @ | Berea | 67-76 | |
| | | 8:00PM | Bethel College | @ | Brescia | 57-81 |  |
| February |
| * | 1 | 7:30PM | Spalding University | @ | Asbury | 65-70 | (OT) |
| | Johnny Leep (Asbury) dished his 700th career assist, already career lead in category |
| * | 2 | 7:30PM | Alice Lloyd | @ | Berea | 68-59 | |
| * | | 9:00PM | Mid-Continent College | @ | Bethel College | 73-97 |  |
| * | 3 | 7:30PM | SLCOP | @ | Asbury | 71-75 | |
| | | 9:00PM | Mid-Continent College | @ | Messenger College | 109-60 | |
| * | 4 | 1:00PM | IU Southeast | @ | Bethel College | 77-78 | |
| * | | 2:00PM | SLCOP | @ | Berea | 60-74 | |
| | | 4:00PM | Brescia | @ | Spalding University | 49-57 | |
| * | | 6:00PM | Alice Lloyd | @ | Mid-Continent College | 94-90 | (OT) |
| * | 6 | 9:00PM | Mid-Continent College | @ | Spalding University | 51-67 | |
| * | 7 | 7:00PM | Bethel College | @ | Spalding University | 63-90 |  |
| | | 7:00PM | Logan Chiropractic | @ | SLCOP | 67-64 | |
| | | 7:00PM | Brescia | @ | University of Illinois at Springfield | 82-92 | (2OT) |
| * | | 7:30PM | Berea | @ | Asbury | 61-88 | |
| | | 7:30PM | UVA-Wise | @ | Alice Lloyd | 58-70 |  |
| * | | 7:30PM | Mid-Continent College | @ | IU Southeast | 62-111 |  |
| | 9 | 7:00PM | Lindsey Wilson | @ | Brescia | 61-50 |  |
| * | | 7:30PM | IU Southeast | @ | Asbury | 78-48 |  |
| | 10 | 7:00PM | Ohio Christian | @ | Asbury | 74-101 | |
| | | 7:00PM | Spalding University | @ | Harris-Stowe State College | 71-55 | |
| * | | 7:30PM | Mid-Continent College | @ | Berea | 71-86 | |
| * | 11 | 3:00PM | Bethel College | @ | Berea | 88-94 | (OT) |
| * | | 5:00PM | Alice Lloyd | @ | IU Southeast | 63-92 |  |
| * | | 5:00PM | Spalding University | @ | SLCOP | 72-48 | |
| * | | 6:00PM | Mid-Continent College | @ | Asbury | 80-83 | |
| | 14 | 7:00PM | Brescia | @ | Bethel College | 82-68 |  |
| | | 7:00PM | Concordia Seminary-St. Louis | @ | SLCOP | 75-79 | |
| * | | 7:30PM | Spalding University | @ | IU Southeast | 54-63 |  |
| * | | 8:00PM | Alice Lloyd | @ | Asbury | 89-72 | |
| * | 16 | 8:00PM | Berea | @ | Spalding University | 56-60 | |
| | 17 | 7:00PM | Cowley County Community College | @ | SLCOP | 68-82 | |
| * | | 8:00PM | Mid-Continent College | @ | Alice Lloyd | 72-96 | |
| * | 18 | 3:00PM | Asbury | @ | Bethel College | 103-87 |  |
| * | | 7:30PM | IU Southeast | @ | Berea | 89-75 |  |
| * | 19 | 4:00PM | Spalding University | @ | Alice Lloyd | 78-66 | |
| | 23 | 2:00PM | Bethel College | vs. | Alice Lloyd | 76-72 | |
| | First Round of KIAC Tournament #3 Alice Lloyd vs. #6 Bethel |
| | | 4:00PM | Mid-Continent College | vs. | Spalding University | 51-92 | |
| | First Round of KIAC Tournament #2 Spalding vs. #7 Mid-Continent |
| | | 6:00PM | Berea | vs. | Asbury | 101-90 | |
| | First Round of KIAC Tournament #4 Asbury vs. #5 Berea |
| | | 8:00PM | SLCOP | vs. | IU Southeast | 57-75 | |
| | First Round of KIAC Tournament #1 IU Southeast vs. #8 SLCOP |
| | 24 | 6:00PM | Bethel College | vs. | Spalding University | 80-97 | |
| | Semifinal #1 - KIAC Tournament |
| | | 8:00PM | Berea | vs. | IU Southeast | 63-93 | |
| | Semifinal #2 - KIAC Tournament |
| | 25 | 2:00PM | Brescia | @ | Park University | 54-64 | |
| | | 8:00PM | Spalding University | vs. | IU Southeast | 62-65 | |
| | Championship Game for KIAC Men's Basketball Tournament |
| | 28 | 7:00PM | Cumberland Univ. | @ | Brescia | 52-56 | |
| March |
| | 9 | 11:15AM | IU Southeast | vs. | MidAmerica Nazarene University | 62-72 | |
| | First Round -NAIA DII National Championship (Point Lookout, Mo.) |
| | 17 | | Asbury | vs. | Roberts Wesleyan College | 60-69 | |
| | Opening Round NCCAA National Tournamnet at Oaklnad City, IN |
| | 18 | | Asbury | vs. | Bethany Lutheran College | 87-97 | |
| | 19 | | Asbury | vs. | Wallla Walla College | 90-87 | |
| | Johnny Leep scores 27 points and adds 12 assists as Asbury finishes 7th at NCCAA National Tournament |